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non-alcoholic fatty liver disease epidemiology microenvironment nonalcoholic steatohepatitis transplantation cholangiocarcinoma direct-acting antiviral immunotherapy hepatitis B hepatitis C liver resection imaging cancer stem cell diagnosis gene cirrhosis biomarker recurrence

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Editorial Board

Editor-in-Chief

  • Guang-Wen Cao
    Chairman, professor, and PhD supervisor at Department of Epidemiology, Second Military Medical University, Shanghai, China.
    Research Interests: Hepatitis B virus, hepatocellular carcinoma, evolution, prediction, prophylaxis, therapeutic option, predicative biomarker, prognostic biomarkers

Executive Chief Editor

  • Giuliano Ramadori
    Professor of Medicine, Gastroenterology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.
    Research Interests: Gene expression, liver cells (hepatocytes, kupffer cells, endothelial cells, stellate cells), pathogenesis, inflammation, cancer development,animal models of liver cancer diagnostic procedures and therapy, COVID-19 diagnostic and treatment, mechanisms of acute-phaseresponse, gastrointestinal cancer diagnostic and endoscopic therapy, systemic cancer therapy, tumor microenviroment analysis, liver diseases diagnostic, therapy, iron metabolism, radiation biology

Honorary Editors-in-Chief

  • Masao Omata
    Department of Gastroenterology, University of Tokyo, Tokyo, Japan.
    Research Interests: Hepatology, gastroenterology, oncology
  • Shu-Kui Qin
    Clinical Oncology Department, Nanjing Jinling Hospital, Nanjing, Jiangsu, China.
    Research Interests: Gastrointestinal cancers, treatment, liver cancer, primary liver cancer

Associate Editors

  • Kenneth Siu Ho Chok
    Department of Surgery, University of Hong Kong, Hongkong, China.
    Research Interests: Hepatocellular carcinoma, liver transplantation, intrahepatic cholangiocarcinoma
  • Jia Fan
    Department of Liver Surgery, Fudan University, Shanghai, China.
    Research Interests: Hepatocellular carcinoma, clinical diagnosis, treatment and basic research of liver cancer
  • Fabio Farinati
    Department of Surgical and Gastroenterological Sciences, Padua University, Padua, Italy.
    Research Interests: Hepatocellular carcinoma, precision medicine, non-alcoholic steatohepatitis, microRNA, locoregional treatments
  • Mark Alan Feitelson
    College of Science and Technology, Department of Biology Temple University, PA, USA.
    Research Interests: Hepatitis B virus, pathogenesis of chronic liver diseases, gut microbiome, autoimmune diseases, short chain fatty acids, development of a synthetic immune system
  • James Fung
    The University of Hong Kong, State Key Laboratory of Liver Research, Hong Kong, China.
    Research Interests: Disease recurrence in liver transplantation, viral hepatitis, liver fibrosis, hepatocellular carcinoma
  • Guido Gerken
    Department of Gastroenterology and Hepatology, University of Essen, Essen, Germany.
    Research Interests: Internal medicine, gastroenterology, hepatology, clinical virology, clinical immunology, endoscopy, liver transplantation, autoimmunity, infectiology, visceral medicine, acute and terminal liver failure, molecular pathomechanisms of liver failure, fibrosis progression of chronic liver diseases, evaluation of mini-laparoscopy for the diagnosis of chronic liver diseases, crohn’s disease, ulcerative colitis, autoimmune hepatitis, viral hepatitis and HIV coinfection, hepatocellular carcinoma, establishment of biomarkers in gastroenterology
  • Salvatore Gruttadauria
    Department of Surgery, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IRCCS-ISMETT), Palermo, Italy.
    Research Interests: Liver resection, liver transplantation, laparoscopic surgery, laparoscopic thermal ablation, living related liver transplantation, living donor
  • Jin-Lin Hou
    Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
    Research Interests: Clinical management of viral hepatitis, molecular virology, immunology of hepatitis B virus (HBV), severe acute respiratory syndrome (SARS) infection
  • Claudio Tiribelli
    Fondazione Italiana Fegato – Italian Liver Foundation NPO, AREA Science Park, Trieste, Italy.
    Research Interests: Bilirubin, neonatal jaundice, metabolic liver diseases, hepatocellular carcinoma, stem cells in hepatocellular carcinoma, crigler-najjar syndrome, translational medicine
  • Allan Tsung
    The Ohio State University Wexner Medical Center, Columbus, OH, USA.
    Research Interests: Tumor microenvironment, metastastases, surgical quality, cancer disparities, minimally invasive surgery, robotic surgery
  • Kai-Chun Wu
    Emergency Room of Digestive Diseases, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Xi'an, Shaanxi, China.
    Research Interests: Gastrointestinal cancers, treatment, liver cancer, gut
  • Osamu Yokosuka
    Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
    Research Interests: hepatocellular carcinoma, hepatitis B/C virus, acute liver, fulminant hepatitis

Editorial Board Members

  • Sang Hoon Ahn
    Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
    Research Interests: Hepatitis B virus, transarterial chemoembolization, radio frequency ablation
  • Luca Aldrighetti
    Hepatobiliary and General Surgery Division, San Raffaele Hospital, Milan, Italy.
    Research Interests: Surgical treatment of hepatobiliary diseases, minimally invasive surgery, resection, cholangiocarcinoma
  • Ping An
    Molecular Genetic Epidemiology Section, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
    Research Interests: Hepatitis B virus-associated hepatocellular carcinoma, viral pathogenesis, biomarkers, therapeutic targets
  • Matias Avila
    Hepatology Program, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
    Research Interests: Molecular mechanisms, carcinogenesis, liver regeneration, liver fibrosis, chronic liver diseases
  • Clara Balsano
    Internal Medicine (MED 09), Department of Life, Health and Environmental Sciences (MESVA), University of L'Aquila, L'Aquila, Italy.
    Research Interests: New immunological treatments, autoimmune hepatitis, role of Hepatitis B virus and Hepatitis B virus viral proteins in tissue damage, biomarkers, nonalcoholic fatty liver disease, steatohepatitis, gender differences, response, innovative treatments
  • Stefano Bellentani
    Gastroenterology and Hepatology Service, Clinica Santa Chiara, Locarno, Switzerland.
    Research Interests: Metabolic associated fatty liver disease, non-alcoholic fatty liver disease, endocrine disorders, sex differences, metabolic syndrome, liver, hypobetalipoproteinemia, dysmetabolism in hepatitis C virus
  • Antonio Bertoletti
    Division Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore City, Singapore.
    Research Interests: Immunopathogenesis, hepatitis C virus infection, SARS-CoV1/2 infections, new immunological based therapies (T cell receptor-redirected T cells), treatment of hepatitis C virus, SARS-CoV-2, hepatocellular carcinoma
  • Stefano Brillanti
    Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
    Research Interests: Hepatocellular carcinoma, hepatitis B/C virus, cirrhosis, non-alcoholic steatohepatitis
  • Elisa Callegari
    Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
    Research Interests: Hepatocellular carcinoma, cirrhosis, transgenic mice, micro RNA, therapy, prophylaxis, liquid biopsies
  • Jian-Guo Chen
    Qidong Liver Cancer Institute; Tumor Institute, Tumor Hospital, Nantong University, Nantong, Jiangsu, China.
    Research Interests: Hepatitis B virus, prevention, HBsAg, survival
  • Amedeo Columbano
    Department of Biomedical Sciences, Unit of Oncology and Molecular Pathology, University of Cagliari, Cagliari, Italy.
    Research Interests: Hepatocellular carcinoma, nuclear receptors, animal models, cell proliferation, NRF2, metabolic reprogramming
  • Hui-Guo Ding
    Department of Gastroenterology and Hepatology, Beijing You An Hospital affiliated to Capital Medical University, Beijing, China.
    Research Interests: Clinical diagnosis, treatment and research of liver cirrhosis, portal hypertension and its complications, early liver cancer diagnosis and screening, ascites, gastrointestinal bleeding, malnutrition, hepatic encephalopathy, pancreatic biliary disease, endoscopic minimally invasive diagnosis and treatment
  • Isabel Fabregat
    Bellvitge Biomedical Research Institute (IDIBELL), CIBEREHD and University of Barcelona, L’Hospitalet, Barcelona, Spain.
    Research Interests: Liver cancer, hepatocellular carcinoma, liver fibrosis, liver regeneration, TGF-beta, EGF, NADP Hoxidases, NOX4, oxidative stress
  • Gen-Sheng Feng
    Department of Pathology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA, USA.
    Research Interests: Liver cancer metastasis, immunotherapy, hepatocarcinogenesis, stem cells, autoimmune diseases
  • Lynn G. Feun
    Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL, USA.
    Research Interests: Hepatocellular carcinoma, biomarkers, clinical trials, immunotherapy
  • Richard S. Finn
    Division of Hematology/Oncology, Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
    Research Interests: Molecular therapies for hepatocellular carcinoma, systemic therapy, therapeutic strategies
  • David Geller
    UPMC Liver Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
    Research Interests: Liver surgery, molecular mechanisms of liver injury, liver cancer signaling mechanisms
  • Brian Kim Poh Goh
    Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.
    Research Interests: Laparoscopic surgery, robotic surgery, liver resection, prognostication, hepatocellular carcinoma
  • Xin-Yuan Guan
    Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
    Research Interests: Stem cells, hepatocellular carcinoma, tumor microenvironment
  • Ho Seong Han
    Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, South Korea.
    Research Interests: Hepatobiliary-pancreatic surgery, hepatocellular carcinoma, pancreas cancer, biliary tract cancer
  • Hie-Won Hann
    Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
    Research Interests: Hepatitis B virus cure drug, biomarkers, risks, hepatocellular carcinoma
  • Hanaa A. Hassan
    Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
    Research Interests: Nutritional therapy dietary antioxidants, natural products, metabolic syndrome, cancer biology, hepatocellular carcinoma, osteoporosis, atherosclerosis, diabetes, obesity
  • Michael A. Heneghan
    Institute of Liver Studies, King's College Hospital, Denmark Hill, London, UK.
    Research Interests: Autoimmune hepatitis, liver transplant, acute liver failure, primary biliary cholangitis
  • Thomas Kietzmann
    University of Oulu, Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, Oulu, Finland.
    Research Interests: Hypoxia, reactive oxygen species (ROS) Cancer, liver metabolism and zonation, cell signaling and transcriptional regulation, hemostasis and fibrinolysis, obesity and diabetes, insulin signaling, protein structure and stability
  • Jin-wook Kim
    Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
    Research Interests: Viral hepatitis B and C, molecular biology, new drugs, clinical trials, liver fibrosis, liver cancer, pathogenesis, treatment
  • John Koskinas
    Medical School National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
    Research Interests: Hepatocellular carcinoma, hepatitis B virus, hepatitis C virus, liver cirrhosis
  • Sandi A. Kwee
    John A. Burns School of Medicine, University of Hawaii at Manoa, HI, USA.
    Research Interests: Molecular imaging, liquid biopsy, hepatocellular carcinoma biomarkers, immunotherapy, chronic liver disease
  • Nan Li
    Department of Hepatic Surgery VI, AnTing District of the Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
    Research Interests: Hepatocellular carcinoma, HBV-DNA, metastasis, transformation, liver transplantation
  • Amedeo Lonardo
    Operating Unit of Metabolic Syndrome, Azienda Ospedaliero-Universitaria di Modena, Ospedale Civile di Baggiovara, Modena, Italy.
    Research Interests: Metabolic associated fatty liver disease, non-alcoholic fatty liver disease, endocrine disorders, sex differences in non-alcoholic fatty liver disease, metabolic syndrome, liver, hypobetalipoproteinemia, dysmetabolism in Hepatitis C virus infection, diabetes in cirrhosis
  • David M. Lubman
    Department of Surgery, The University of Michigan, Ann Arbor, MI, USA.
    Research Interests: Hepatocellular carcinoma, liver cancer, cancer biomarkers, masss pectrometry, glycosylation, exosomes, amino acid variants
  • Chun-Hong Ma
    School of Basic Medical Science, Shandong University, Jinan, Shandong, China.
    Research Interests: Immune regulation, liver diseases, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, Immunology
  • David C. Madoff
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
    Research Interests: Interventional radiology, liver cancer, thermal ablation, embolotherapy, liver regeneration
  • Fabio Marra
    Dipartimento di Medicina Sperimentale Clinica, University of Florence, Florence, Italy.
    Research Interests: Cholangiocarcinoma, liver transplant, non-alcoholic steatohepatitis
  • Geoff McCaughan
    School of Medicine, University of Sydney, Sydney, Australia.
    Research Interests: Immunopathogenesis, chronic liver disease, liver autoimmunity, liver transplantation, hepatitis B and C virus, hepatocellular carcinoma
  • Manuela Merli
    Department of Translational and Precision medicine, "Sapienza" University of Rome, Rome, Italy.
    Research Interests: Liver cirrhosis, portal hypertension, hepatic encephalopathy, bacteria infections in chronic liver disease, malnutrition and sarcopenia in liver disease, liver transplantation
  • Gabriele Missale
    Unit of Infectious Diseases and Hepatology, University Hospital of Parma, Parma, Italy.
    Research Interests: Hepatocellular carcinoma, tumor Immune microenvironment, hepatitis B virus, hepatitis C virus, Immuneresponse, Tcell, NK cell
  • Bruno Nardo
    Department of Medical and Surgical Sciences (DIMEC), S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
    Research Interests: Surgical oncology, hepatobiliary pancreatic surgery, liver transplantation, experimental surgery, liver regeneration
  • Necati Örmeci
    Department of Gastroenterology, Ankara University Medical School, Ankara, Turkey.
    Research Interests: Hepatitis B virus, hepatitis C virus, hepatitis D virus, hepatocellular carcinoma, hydatidCyst, portal hypertension
  • Rosa Maria Pascale
    Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
    Research Interests: Hepatocarcinogenesis, model, genes alterations, signal transductions, targeting therapy
  • Tao Peng
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
    Research Interests: Hepatocellular carcinoma, biomarkers, hepatitis B virus, liver surgery
  • Patrizia Pontisso
    Department of Medicine, University of Padua, Padua, Italy.
    Research Interests: Liver cancer, cirrhosis, diagnostic markers, molecular biology of liver tumors, hepatocellular carcinoma, cholangiocarcinoma
  • Xingshun Qi
    Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China.
    Research Interests: Liver cirrhosis, portal hypertension, hepatocellular carcinoma
  • Chunfeng Qu
    National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
    Research Interests: Hepatocellular carcinoma, HBsAg, hepatitis B virus, prevention
  • Lorenza Rimassa
    Department of Biomedical Sciences, Humanitas University, Milan, Italy.
    Research Interests: Hepatocellular carcinoma, biliary tract cancer, cholangiocarcinoma, liver cancer, new drugs, targeted agents, immunotherapy, biomarkers
  • Dalbir Singh Sandhu
    Department of Gastroenterology and Hepatology, MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH, USA.
    Research Interests: Liver cancer, biliary cancers, endoscopy
  • Devanand U. Sarkar
    Virginia Commonwealth University Health System, Richmond, USA.
    Research Interests: Molecular mechanism, hepatocellular carcinoma, novel, targeted and effective therapy for hepatocellular carcinoma
  • Ankur Sharma
    Harry Perkins Institute of Medical Research and Curtin University, Perth, Western Australia, Australia.
    Research Interests: Single cell genomics, tumor heterogeneity, oncofetal ecosystem, macropahge, liver cancer, tumor Immunology, spatial transcriptomics, artificial intelligence
  • Feng Shen
    Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
    Research Interests: Intrahepatic cholangiocarcinoma, treatment of hepatobiliary and pancreatic diseases
  • Dar-In Tai
    Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Chang Gung University, Taoyuan, Taiwan.
    Research Interests: hepatitis B virus, genetic polymorphism, hepatocellular carcinoma family, elastography, liver ultrasound
  • Rolf Teschke
    Department of Internal Medicine II, Division of Gastroenterology and Hepatology, Klinikum Hanau, Hanau, Germany.
    Research Interests: Clinical hepatology, DILI, HILI, RUCAM, drugs, herbs, alcohol, aliphatic halogenated hydrocarbons
  • Roberto Ivan Troisi
    Division of HPB, Minimally Invasive and Robotic Surgery, Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
    Research Interests: Hepatocellular carcinoma, laparoscopic surgery, robotic surgery, robotic donor hepatectomy, liver transplantation, living donor liver transplant
  • Georgios Tsoulfas
    Surgery, Aristoteleion University of Thessaloniki, Thessaloniki, Greece.
    Research Interests: Hepatobiliary surgery, primary and secondary hepatic malignancies, ischemia/reperfusion injury, solid organ transplantation, medical/surgical education, 3D printing
  • Hong Tu
    Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.
    Research Interests: Hepatitis B virus-related hepatocellular carcinoma carcinogenesis, hepatocellular carcinoma prediction, hepatocellular carcinoma prevention, tumor marker of hepatocellular carcinoma
  • Erica Villa
    Division of Gastroenterology, University of Modena and Reggio Emilia, Modena, Italy.
    Research Interests: Hepatitis C virus, cirrhosis, direct-acting antiviral therapy, genotype, hepatitis B virus, platelets, portal hypertension, coagulation
  • Rong-Qian Wu
    Research Institute of Advanced Surgical Technology and Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Hong-Ping Xia
    Department of Pathology, College of Basic Medicine, Nanjing Medical University, Nanjing Province, China & Laboratory of Cancer Genomics, National Cancer Center Singapore, Singapore.
    Research Interests: Viral and non-viral hepatocellular carcinoma, target therapy, molecular pathology, noncoding RNAs, immunotherapy
  • Yong-Bing Xiang
    Shanghai Jiao Tong University School of Medicine, Shanghai Cancer Institute, Shanghai, China.
    Research Interests: Cancer statistics, cancer epidemiology, survival analysis, meta-analysis, cancer prevention
  • Jin-Liang Xing
    President of Tumor Markers Committee of China Anti-Cancer Association, Xi’an, Shaanxi, China.
    Research Interests: Hepatocellular carcinoma, molecular mechanism, circulating cell-free DNA, mtDNA, mitochondria, biomarkers
  • Fu Yang
    Department of Medical Genetics, Second Military Medical University, Shanghai, China.
    Research Interests: Hepatocellular carcinoma, epigenetics, RNA post-transcriptional modification, tumor energy metabolism, tumor microenvironment, tumor immunity
  • Dengfu Yao
    Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
    Research Interests: Early diagnosis and pathogenesis of hepatocellular carcinoma, hepatocarcinogenesis, biomarkers
  • Jian-Hua Yin
    Department of Epidemiology, Second Military Medical University, Shanghai, China.
    Research Interests: Hepatitis B virus, hepatocellular carcinoma, evolution, prediction, prophylaxis, therapeutic option, biomarker
  • Seung-Kew Yoon
    Cancer Hospital, Seoul St. Mary's hospital, The Catholic University of Korea, Seoul, South Korea.
    Research Interests: Hepatitis B virus, hepatitis C virus, metastasis, HBsAg, genotype, chemoembolization, transarterial chemoembolization, liver transplant
  • Hong-Wei Zhang
    Department of Epidemiology, Military Medical University of Navy, Shanghai, China.
    Research Interests: Cancer epidemiology, hepatocarcinoma, prostate cancer, molecular epidemiology, prevention

Founding Editor-in-Chief

  • Joseph F. Buell
    Department of Surgery, Mission Health, HCA North Carolina Division, University of North Carolina, Asheville, NC, USA.
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