fig1

Liver regeneration: metabolic and epigenetic regulation

Figure 1. Summary of epigenetic modifications associated with liver regeneration[84,86,112,126-129]. A: Table representing the comparison of a quiescent and regenerating liver. “↑” represents an increase in expression and “↓” represents a decrease in expression; B: A schematic representation of the changes associated with the transition of a quiescent liver to a regeneration phase. During regeneration, a reorganization of histone modifications (primarily, acetylation, and methylation) and DNA methylation occurs. However, a detailed epigenetic code for liver regeneration is yet to be decoded

Hepatoma Research
ISSN 2454-2520 (Online) 2394-5079 (Print)

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Portico

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