fig6

Figure 6. TP53 mutation is a poor prognostic factor and correlates with higher ID1 expression. (A) PDAC patients in the TCGA dataset with tumor p53 mutation (63%) were compared to p53 wildtype for disease free-survival (DFS). Patients with p53 mutations had significantly worse DFS than p53 wildtype, P = 0.003. (B) ID1 mRNA expression was compared in p53 mutated tumors vs. p53 wildtype tumors from the TCGA PDAC dataset. ID1 expression was higher in the p53 mutated patients *P < 0.05.