fig2

Figure 2. Microbial changes by elevated HbA1c. Principal coordinate plot of microbiome data grouped by the presence of elevated (≥ 6.5%) HbA1c or low HbA1c (< 6.5%). Ellipsis represent 95% confidence interval (A). Alpha diversity as measured by Shannon index between patients with high or low HbA1c (B). Taxonomic plot of genera present in patients with high or low HbA1c. Only genera with a relative abundance ≥ 1% are shown (C). Differential abundance testing by DESeq2 showing genera that are different between patients with elevated HbA1c as compared to those with low HbA1c (D).