fig5
From: Role of CD4+ T-cells in the pathology of non-alcoholic fatty liver disease and related diseases
Figure 5. Summary of the contribution of Tregs in NAFLD and the related pathologies. The ellipse on the left shows the dynamics of Tregs in peripheral blood and adipose tissue in obesity and type 2 diabetes (T2DM) in humans, while the ellipse on the right shows the dynamics of Tregs in adipose tissue, mesenteric lymph nodes, and small intestinal mucosa in obese mice. The central square summarizes the Tregs dynamics in the peripheral blood and liver tissue and cytokine dynamics in NAFLD. The left side shows the dynamics in humans, and the right side shows the dynamics in mice. NAFLD: Non-alcoholic fatty liver disease; NAFL: non-alcoholic fatty liver; NASH: non-alcoholic steatohepatitis; Treg: regulatory T-cell.
