fig1

Imaging biomarkers for predicting poor prognosis of hepatocellular carcinoma: a review

Figure 1. A 48-year-old male with a pathologically confirmed HCC with MVI. A 7.8 cm × 6.0 cm tumor in the right posterior hepatic section shows slight hyperintensity on T2-weighted image (A), hypo-intensity relative to the surrounding liver parenchyma in hepatobiliary phase (B), and restricted diffusion on the DWI with a b-value of 700 s/mm2 (C). MK map (D) shows higher signal intensity of tumor compared with that of background liver parenchyma. ADC (E) and MD (F) maps show lower signal intensity compared with that of liver parenchyma. The calculated mean values of MK, ADC, and MK for the tumor were 0.99, 1.10 × 10-3 mm2/s, and 1.28 mm2/s, respectively. The pathological results after tumor resection demonstrated HCC [Edmondson-Steiner (III) with positive MVI (G)]. HCC: hepatocellular carcinoma; DWI: diffusion-weighted imaging; ADC: apparent diffusion coefficient; MD: mean diffusion; MK: mean apparent kurtosis coefficient

Hepatoma Research
ISSN 2454-2520 (Online) 2394-5079 (Print)

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