fig1

Figure 1. Schematic diagram of viral activity and viral biomarkers. The red box presents the period after liver transplantation. The blue bar presents the viral activity, with continual decline after liver transplantation. Black represents positive, white represents negative, and gray represents a gradient from high to low (dark to light). The green numbers represent a cross-section of the biomarkers after transplant: (1) HBsAg positive + HBV DNA negative; (2) HBsAg negative (but detectable with highly sensitive quantitative assays) + HBV DNA negative; and (3) HBsAg negative + HBV DNA negative (but with persistent integrated HBV DNA and cccDNA).