fig30

Evaluating normalization approaches for the better identification of aberrant microRNAs associated with hepatocellular carcinoma

Supplementary Figure 3. Comparisons of the consistency and discrepancy of miRNA panels identified using global mean or top stable miRNAs as normalizers. (A) Using the mean of global miRNAs or miR-30c/miR-126 as normalizers, 7 dysregulated miRNAs (miR-183, miR-1180, miR-18a, miR-130b#, miR-339-3p, miR-21 and miR-106a) were identified in HCC tumor tissues. (B) Using the mean of global miRNAs or miR-30c/miR-30b as normalizers, 3 dysregulated oncogenic miRNAs (miR-183, miR-18a and miR-106a) were identified. These miRNAs were not identified using 3 endogenous ncRNAs as normalizer

Hepatoma Research
ISSN 2454-2520 (Online) 2394-5079 (Print)

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