fig3

Evaluating normalization approaches for the better identification of aberrant microRNAs associated with hepatocellular carcinoma

Figure 3. InteractiVenn determination of the consistent and discrepant microRNA (miRNA) panels identified using different normalization strategies. Using the mean of miRNAs and 2 stable miRNAs as normalizers (A), 14 miRNAs (miR-196b, miR-183, miR-182, miR-10b#, miR-18a, miR-106a, miR-139-5p, miR-144#, miR-214, miR-486, miR-199a-3p, miR-511, miR-424 and miR-125b) were consistently identified as dysregulated in hepatocellular carcinoma tumor tissue. (B) Compared to the panel identified using endogenous controls as the normalizer, a total of 11 miRNAs (miR-196b, miR-182, miR-10b#, miR-139-5p, miR-144#, miR-214, miR-486, miR-199a-3p, miR-511, miR-424 and miR-125b) were consistently identified by all normalization strategies

Hepatoma Research
ISSN 2454-2520 (Online) 2394-5079 (Print)

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Portico

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https://www.portico.org/publishers/oae/