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Figure 2. Hepatocellular carcinoma (HCC) "tumor specific" miRNA expression patterns (fold-changes and standard errors) compared to 8 other types of solid tumors. Three miRNAs (miR-24-1, miR-130a and miR-505) were significantly down-regulated in HCC with over 2-fold changes. Although the expression pattern of 3 miRNAs was consistently repressed in kidney renal cell carcinoma (KIRC) and prostate adenocarcinoma (PRAD), none were statistically significant. An up-regulated expression pattern was observed for the 3 miRNAs in head and neck squamous cell carcinoma (HNSC), lung adenocarcinoma (LUAD) and stomach adenocarcinoma (STAD), but also no significant difference. Both up- and down-regulation patterns were obtained for the 3 miRNAs in female breast invasive carcinoma (BRCA), lung squamous cell carcinoma (LUSC) and thyroid carcinoma (THCA), suggesting their tumor specificity