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    Review| Open Access

    Thermal ablation of large unresectable hepatocellular carcinoma in cirrhotic patients

    Giovan Giuseppe Di Costanzo, Raffaella Tortora, Anna Opramolla, Marco Guarracino

    Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies worldwide. Surgery is the mainstay of treatment, but less than 20%-30% of patients are good candidates. Actually, thermal ablation is considered the best treatment with curative intent for cirrhotic patients with... Read more

    This article belongs to the Special Issue Management of Hepatocellular Carcinoma Hepatoma Res 2018;4:53. | doi:10.20517/2394-5079.2018.56
    Published on: 17 Sep 2018  | Viewed:13  | Downloaded:1
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    Review| Open Access

    The fibroblast growth factor receptor pathway in hepatocellular carcinoma

    Joycelyn Jie Xin Lee, Su Pin Choo

    Hepatocellular carcinoma is the third most common cause of cancer-related death globally and portends a poor prognosis. The fibroblast growth factor receptor (FGFR) pathway is increasingly acknowledged to play a role in the pathogenesis of hepatocellular carcinoma (HCC) and is postulated to be... Read more

    This article belongs to the Special Issue Molecular Mechanism of Hepatocellular Carcinoma Hepatoma Res 2018;4:52. | doi:10.20517/2394-5079.2018.42
    Published on: 13 Sep 2018  | Viewed:82  | Downloaded:8
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    Review| Open Access

    Cancer immunotherapy for hepatocellular carcinoma

    Joo-Ho Lee, Soo-Yeon Oh, Jin Yong Kim, Naoshi Nishida

    Most hepatocellular carcinomas (HCCs) arise on a background of chronically inflamed liver, and thus are considered typical immunogenic cancers. Although there have been advances in treatment options for HCC, many patients still struggle with a limited chance of survival requiring further... Read more

    This article belongs to the Special Issue Management of Hepatocellular Carcinoma Hepatoma Res 2018;4:51. | doi:10.20517/2394-5079.2018.78
    Published on: 10 Sep 2018  | Viewed:259  | Downloaded:25
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    Review| Open Access

    Hepatic resection for hepatocellular carcinoma

    Shun Yamaguchi, Taichiro Kosaka, Susumu Eguchi

    Hepatic resection has become the standard treatment of primary liver cancer. Indications for hepatic resection in patients with hepatocellular carcinoma (HCC) vary greatly between Japan and other countries because the clinical practice guidelines for HCC defined by the Japan Society of Hepatology... Read more

    This article belongs to the Special Issue Management of Hepatocellular Carcinoma Hepatoma Res 2018;4:50. | doi:10.20517/2394-5079.2018.68
    Published on: 22 Aug 2018  | Viewed:455  | Downloaded:38
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    Review| Open Access

    Hypofractionated ablative radiation therapy for hepatocellular carcinoma: practical considerations and review of the literature

    Marsha Reyngold, Eugene J. Koay, Christopher H. Crane

    Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. The prognosis for patients who present with inoperable primary liver tumors is poor with median survival times of 12 months or less. Tumor-related liver failure is a common cause of mortality, underscoring the importance... Read more

    This article belongs to the Special Issue Management of Hepatocellular Carcinoma Hepatoma Res 2018;4:49. | doi:10.20517/2394-5079.2018.84
    Published on: 20 Aug 2018  | Viewed:725  | Downloaded:66
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    Review| Open Access

    Chitinase-3-like protein 1 as a predictor for the progression or regression of liver fibrosis

    Biaoyang Lin, Shengjun Wu, Yunhua Liu, Longgen Liu, Saadiya Mushtaq

    Liver fibrosis is a wound-healing response of liver cells to chronic injuries caused by viral infections, including hepatitis B virus (HBV), hepatitis C virus (HCV), toxins, and alcohol abuse. The ability to stage diseases for treatment naïve patients to initiate proper medical procedures and... Read more

    Hepatoma Res 2018;4:48. | doi:10.20517/2394-5079.2018.19
    Published on: 17 Aug 2018  | Viewed:177  | Downloaded:14
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    Review| Open Access

    Laparoscopic liver resection for hepatocellular carcinoma

    Massimo Giacca, Daniel Cherqui

    Hepatocellular carcinoma (HCC) represents the most common indication of laparoscopic liver resection (LLR). It must be acknowledged that most series concern minor hepatectomies for peripheral lesions located in favorable segments, and such procedures are now performed in the majority of HPB... Read more

    This article belongs to the Special Issue Management of Hepatocellular Carcinoma Hepatoma Res 2018;4:47. | doi:10.20517/2394-5079.2018.79
    Published on: 17 Aug 2018  | Viewed:385  | Downloaded:31
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    Review| Open Access

    Screening for hepatocellular carcinoma: summary of current guidelines up to 2018

    Nevin Yilmaz, Ugur Eser Yilmaz, Kaya Suer, Vedat Goral, Nedim Cakir

    Hepatocellular carcinoma (HCC) is one of the leading causes of cancer related to worldwide death with a great geographical variation. To be eligible for curative therapy at the time of diagnosis is important. However, the majority of cases are diagnosed at late stages. This can be achieved with... Read more

    This article belongs to the Special Issue What More We can do on Hepatitis C? Hepatoma Res 2018;4:46. | doi:10.20517/2394-5079.2018.49
    Published on: 16 Aug 2018  | Viewed:431  | Downloaded:33
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    Opinion| Open Access

    Elimination of hepatitis from Pakistan by 2030: is it possible?

    Yasir Waheed, Masood Siddiq

    Globally 71 million people are living with hepatitis C virus (HCV) out which 7.1 million (10%) are present in Pakistan. Genotype 3 is the most common HCV type in the country. World Health Organization is working with health authorities in different countries for effective control of HCV, to... Read more

    This article belongs to the Special Issue What More We can do on Hepatitis C? Hepatoma Res 2018;4:45. | doi:10.20517/2394-5079.2018.58
    Published on: 14 Aug 2018  | Viewed:412  | Downloaded:16
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    Review| Open Access

    Exosome-based liquid biopsy in the management of hepatocellular carcinoma

    Aparna Jayachandran, Sasidhar Venkata Manda, Ritu Shrestha, Kim R. Bridle, Prashanth Prithviraj, Darrell H. G. Crawford

    Hepatocellular carcinoma (HCC) commonly presents at an advanced stage due to the lack of efficient early screening tools. Early, non-invasive biomarkers useful in the diagnosis and prognosis of HCC would be of significant benefit for HCC management. Development of exosome-based liquid biopsy as a... Read more

    This article belongs to the Special Issue Management of Hepatocellular Carcinoma Hepatoma Res 2018;4:44. | doi:10.20517/2394-5079.2018.59
    Published on: 13 Aug 2018  | Viewed:460  | Downloaded:61
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