Hot Keywords
non-alcoholic fatty liver disease epidemiology microenvironment nonalcoholic steatohepatitis transplantation cholangiocarcinoma direct-acting antiviral immunotherapy hepatitis B hepatitis C liver resection imaging cancer stem cell diagnosis gene cirrhosis biomarker recurrence

Topic: SBRT and Immunotherapy for the Management of HCC: A Recent Appraisal

A special issue of Hepatoma Research

ISSN 2454-2520 (Online), ISSN 2394-5079 (Print)

Submission deadline: 30 Dec 2019

Guest Editor(s)

  • Jia Fan, MD
    Department of Liver Surgery, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai 200032, China.
    Department of Molecular Cell Biology, Institute of Biomedical Sciences, Fudan University, Shanghai 200032, China.


Special Issue Introduction

Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, leading to more than 700 thousand deaths annually. In recent years, immunotherapy has emerged as a novel, effective systemic treatment for advanced HCC, which can potentially suppress tumor recurrence and metastasis. However, the objective response rate of simply immunologic agent treatment for HCC is still unsatisfactory. The combination of conventional treatments including stereotactic body radiation therapy (SBRT) with specific immunotherapeutic approaches may dramatically improve outcome of HCC patients. Moreover, the advancement of SBRT techniques has allowed for a safer administration of higher levels of dose to liver cancer while minimizing the potential liver toxicities. In this edition of Hepatoma Research, we will discuss new advances in SBRT, immunotherapy, and combined strategies for the treatment of patients with liver cancer.

Submission Deadline

30 Dec 2019

Submission Information

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to
For Online Submission, please login at
Submission Deadline: 30 Dec 2019
Contacts: Haidi Ding, Assistant Editor,

Published Articles

© 2016-2022 OAE Publishing Inc., except certain content provided by third parties