Topic: SBRT and Immunotherapy for the Management of HCC: A Recent Appraisal

A special issue of Hepatoma Research

ISSN 2454-2520 (Online), ISSN 2394-5079 (Print)

Submission deadline: 30 Dec 2019

Guest Editor(s)

  • Jia Fan, MD
    Department of Liver Surgery, Zhongshan Hospital, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Fudan University, Shanghai 200032, China.
    Department of Molecular Cell Biology, Institute of Biomedical Sciences, Fudan University, Shanghai 200032, China.


Special Issue Introduction

Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, leading to more than 700 thousand deaths annually. In recent years, immunotherapy has emerged as a novel, effective systemic treatment for advanced HCC, which can potentially suppress tumor recurrence and metastasis. However, the objective response rate of simply immunologic agent treatment for HCC is still unsatisfactory. The combination of conventional treatments including stereotactic body radiation therapy (SBRT) with specific immunotherapeutic approaches may dramatically improve outcome of HCC patients. Moreover, the advancement of SBRT techniques has allowed for a safer administration of higher levels of dose to liver cancer while minimizing the potential liver toxicities. In this edition of Hepatoma Research, we will discuss new advances in SBRT, immunotherapy, and combined strategies for the treatment of patients with liver cancer.


Chen Dong  Tsinghua University, Beijing, China.
Antonio Bertoletti  Duke-NUS Medical School Singapore, Singapore City, Singapore.
Aparna Jayachandran&Ritu Shrestha  Greenslopes Private Hospital, Brisbane, Australia.
Liliana Montella  "S.Maria delle Grazie" Hospital Pozzuoli (Naples)- ASL Naples 2 Nord, Italy.
Chun-Hong Ma  Shandong University, Jinan, China.
Ming Chen&Ning Zhou  Zhejiang Cancer Hospital, Hangzhou, China.
Chunfeng Qu  National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hong Yao  XuZhou Medical University, Xuzhou, China.
Yong Zeng  West China Hospital of Sichuan University, Chengdu, China.
Yu-Min Li  Key Laboratory of Digestive System Tumors of Gansu, Lanzhou, China.
Xun-Di Xu  Second Xiangya Hospital of Central-South University, Changsha, China.
Shu-Qun Cheng&Xiu-Ping Zhang  The National Research Cooperative Group for Diagnosis and Treatment of Hepatocellular Carcinoma with Tumour Thrombus, Shanghai, China.
Xue-Fu Wang  Anhui Medical University, Hefei, China.
The list is arranged in no particular order and being updated.

Submission Deadline

30 Dec 2019

Submission Information

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Submission Deadline: 30 Dec 2019
Contacts: Haidi Ding, Assistant Editor,

Published Articles