Topic: New Insights in Liver Cancer

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A special issue of Hepatoma Research  (Print ISSN:2394-5079; Online ISSN:2454-2520).

Deadline for manuscript submissions: 30 Sep 2018

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Guest Editor(s)

  • Clara Balsano, MD
    Internal Medicine (MED 09), Department of Life, Health and Environmental Sciences (MESVA), University of L'Aquila, L'Aquila, Italy.

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Submission Information:

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to http://hrjournal.net/pages/view/author_instructions
For Online Submission, please login at http://www.editorialmanager.com/hres/default.aspx
Submission Deadline: 30 Sep, 2018
Contacts: Siqi Li, Assistant Editor, editor001@hrjournal.net

Published Articles Download All Articles
  • Stemness features in liver cancer

    Margherita Correnti , Richell Booijink , Giovanni Di Maira , Chiara Raggi , Fabio Marra
    Heterogeneity is a cardinal hallmark of cancer, including primary liver cancer (PLC), and occurs at different layers including putative cell-of-origin. Current evidence suggests that within cellular subpopulations in PLC there are stem-like cells, the cancer stem cells (CSCs). The CSC concept has been recently proposed as an explanation of such intra-tumor heterogeneity. According to this... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:69. | doi:10.20517/2394-5079.2018.96
    Published on: 5 Nov 2018  | Viewed:177  | Downloaded:9
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  • Role of the contrast-enhanced ultrasoud in the diagnosis of HCC in cirrhotic liver

    Francesco Loria , Antonello Parlati , Giuseppe Loria , Luciano Frosina , Giuseppe Crea , Salvatore Basile , Caterina Alessio , Giuseppe Di Leo , Adele De Caridi , Vittorio Maschio , Nicola Zizzi , Orazio Trapuzzano , Salvatore Giuseppe Galea
    The development of second generation ultrasound (US) contrast-medium and specific imaging techniques with dedicated softwares, allows to observe the liver perfusion in real time, becoming an useful and less invasive method to describe precisely the vascularization of hepatic lesions. This significantly increased the ability of US to detect and characterize focal liver lesions. The aim of this... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:59. | doi:10.20517/2394-5079.2018.75
    Published on: 28 Sep 2018  | Viewed:493  | Downloaded:29
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  • New insights on hepatocellular carcinoma: epidemiology and clinical aspects

    Claudio Puoti
    Primary liver cancer represents the 4th most common tumor in males (4% of all cancers) and the 7th most common tumor in females (2.3% of all cancers), with a prevalence of 53/100,000 in males and 22/100,000 in females (male-to-female ratio = 2:1). In the majority of the cases, hepatocellular carcinoma (HCC) develops in patients with cirrhosis and thus the risk factors for HCC and chronic liver... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:57. | doi:10.20517/2394-5079.2018.67
    Published on: 21 Sep 2018  | Viewed:320  | Downloaded:30
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  • Fat and hepatocellular carcinoma

    Clara Balsano , Cristiana Porcu , Silvia Sideri , Simona Tavolaro
    Obesity and diabetes are associated with the onset of hepatocellular carcinoma (HCC). These two illnesses correlate also with the development of non-alcoholic fatty liver disease (NAFLD). Currently, NAFL is considered the leading form of chronic liver disease in the Western industrialized countries. Insulin resistance is the common pathogenic factor among these three pathologies. NAFL is... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:38. | doi:10.20517/2394-5079.2018.51
    Published on: 25 Jul 2018  | Viewed:1703  | Downloaded:149
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  • Pro-oncogenic role of SerpinB3 in hepatocellular carcinoma

    Andrea Martini , Patrizia Pontisso
    Hepatocellular carcinoma (HCC) is one of the most relevant sanitary problems for its prevalence and poor prognosis. This tumor is characterized by highly heterogeneous features, both at clinical and molecular level. SerpinB3 (squamous cell carcinoma antigen-1 or SCCA1) is a serine-protease inhibitor that protects cells from oxidative stress conditions, but in chronic liver damage it may lead to... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:28. | doi:10.20517/2394-5079.2018.50
    Published on: 29 Jun 2018  | Viewed:523  | Downloaded:37
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  • HCV clearance by direct antiviral therapy and occurrence/recurrence of hepatocellular carcinoma: still an issue?

    Francesco Paolo Russo , Martina Tessari , Angela Imondi , Erica Nicola Lynch , Fabio Farinati
    New regimens with direct-acting antivirals (DAAs) agents have changed both efficacy and safety of hepatitis C virus (HCV)-treatment, as almost all patients can be treated and cured at any stage of liver disease. The rates of sustained virological response to currently available combinations exceed 95% in real-life practice. However, conflicting results have been produced on the... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:25. | doi:10.20517/2394-5079.2018.52
    Published on: 27 Jun 2018  | Viewed:801  | Downloaded:99
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  • Time for hepatocellular carcinoma immunotherapy: insights for successful clinical applications in this challenging tumor

    Gabriele Missale , Elisabetta Cariani
    The multiplicity and phenotype of intratumoral immune infiltrate have been shown to influence the clinical outcome of hepatocellular carcinoma (HCC), thus providing a strong rationale to therapeutic interventions aimed at restoring the dysfunctional immune response against the tumor. Improving the knowledge of the complex interactions between transformed hepatocytes, nonparenchymal resident... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:22. | doi:10.20517/2394-5079.2018.72
    Published on: 25 Jun 2018  | Viewed:760  | Downloaded:72
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  • Intrahepatic cholangiocarcinoma: review and update

    Vincenzo Cardinale , Maria Consiglia Bragazzi , Guido Carpino , Sabina Di Matteo , Diletta Overi , Lorenzo Nevi , Eugenio Gaudio , Domenico Alvaro
    Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies that could develop at any level from the biliary tree. CCA is currently classified into intrahepatic (iCCA), perihilar and distal on the basis of its anatomical location. Of note, these three CCA subtypes have common features but also important inter-tumor and intra-tumor differences that can affect the pathogenesis and outcome.... Read more
    This article belongs to the Special Issue New Insights in Liver Cancer
    Hepatoma Res 2018;4:20. | doi:10.20517/2394-5079.2018.46
    Published on: 19 Jun 2018  | Viewed:1707  | Downloaded:198
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Hepatoma Research ISSN 2454-2520 (Online), ISSN 2394-5079 (Print)
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