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  • image 20 Jul 2018 Original Article| Open Access

    Immunohistochemistry of the circadian clock in mouse and human vascular tissues

    Ciprian B. Anea, Ana M. Merloiu, David J. R. Fulton, Vijay Patel, R. Dan Rudic

    Aim: The circadian clock is a molecular network that controls the body physiological rhythms. In blood vessels, the circadian clock components modulate vascular remodeling, blood pressure, and signaling. The goal in this study was to determine the pattern of expression of circadian clock proteins...

    Vessel Plus [HTML] [PDF] Viewed:805 Downloaded:54
  • image 19 Jul 2018 Original Article| Open Access

    New insights into the role of intra-tumor genetic heterogeneity in carcinogenesis: identification of complex single gene variance within tumors

    Bruce Gottlieb, Farbod Babrzadeh, Kathleen Klein Oros, Carlos Alvarado, Chunlin Wang, Baback Gharizadeh, Mark Basik, Celia M.T. Greenwood, Lenore K. Beitel, Mark Trifiro

    Aim: Present cancer hypotheses are almost all based on the concept that accumulation of specific driver gene mutations cause carcinogenesis. The discovery of intra-tumor genetic heterogeneity (ITGH), has resulted in this hypothesis being modified by assuming that most of these ITGH mutations are...

    Journal of Cancer Metastasis and Treatment [HTML] [PDF] Viewed:927 Downloaded:99
  • image 9 Jul 2018 Review| Open Access

    Percutaneous coronary intervention in the elderly: current updates and trends

    Mohammed J. Arisha, Dina A. Ibrahim, Ahmed A. Abouarab, Mohamed Rahouma, Mohamed K. Kamel, Massimo Baudo, Kritika Mehta, Mario F. L. Gaudino

    Ischemic heart disease is the leading cause of death with acute coronary syndrome accounting for more than 30% of causes of mortality in the elderly population. The rate of growth of the older segment of the population has increased exponentially and will become more pronounced in the future....

    Vessel Plus [HTML] [PDF] Viewed:1329 Downloaded:87
  • image 5 Jun 2018 Review| Open Access

    Research into biodegradable polymeric stents: a review of experimental and modelling work

    Tianyang Qiu, Liguo Zhao

    Bioresorbable stents (BRSs) are regarded as the next-generation medical devices to treat blocked or diseased arteries. The use of BRSs aims to reduce the risk of late stent thrombosis and long-term tissue inflammation associated with permanent metallic stents. BRSs are designed to relieve...

    Vessel Plus [HTML] [PDF] Viewed:1299 Downloaded:70
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  • image 37950 Topic: Infectious Disease of Central Nervous System| Open Access

    Current diagnosis and treatment of cryptococcal meningitis without acquired immunodeficiency syndrome

    Xiao-Su Guo, Hui Bu, Jun-Ying He, Yue-Li Zou, Yue Zhao, Yuan-Yuan Li, Jun-Zhao Cui, Ming-Ming Zheng, Wei-Xin Han, Ze-Yan Zhao

    Cryptococcal meningitis (CM) is a central nervous system infectious disease caused by Cryptococcus. It is the most common fungal infection in the central nervous system, accounting for about 48% of fungal infection. The disease occurs mainly in acquired immunodeficiency syndrome (AIDS) patients...

    Neuroimmunology and Neuroinflammation [HTML] [PDF] Viewed:37950 Downloaded:459
  • image 255894 Review| Open Access

    Long non-coding RNAs as key regulators of cancer metastasis

    Pratirodh Koirala, De-Hong Zou, Yin-Yuan Mo

    The recent advances in functional genomics have discovered that a large number of long non-coding RNAs (lncRNAs) are pervasively transcribed from the human genome. Increasing evidence further indicates that lncRNAs are important for gene expression during cell differentiation and development...

    Journal of Cancer Metastasis and Treatment [HTML] [PDF] Viewed:255894 Downloaded:795
  • image 30421 Topic: Biomaterials for Plastic and Aesthetic Surgery| Open Access

    Intradermal fillers for minimally invasive treatment of facial aging

    Zhi Yuan (William) Lin, Vishva Shah, Arvind Dhinakar, Lara Yildirimer, Wen-Guo Cui, Xin Zhao

    The ever-increasing interest in retaining a youthful physical appearance has facilitated the development of various minimally invasive dermatological techniques. The use of intradermal fillers can be incorporated into dermatological practices with minimal overhead costs. This strategy addresses...

    Plastic and Aesthetic Research [HTML] [PDF] Viewed:30421 Downloaded:1215
  • image 62821 Review| Open Access

    Hepatitis B virus molecular biology and pathogenesis

    R. Jason Lamontagne, Sumedha Bagga, Michael J. Bouchard

    As obligate intracellular parasites, viruses need a host cell to provide a milieu favorable to viral replication. Consequently, viruses often adopt mechanisms to subvert host cellular signaling processes. While beneficial for the viral replication cycle, virus-induced deregulation of host...

    Hepatoma Research [HTML] [PDF] Viewed:62821 Downloaded:1632
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